Sarah-Kate Templeton, Health Editor
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THE first genetic test for prostate cancer, which kills 10,000 men every year in Britain, will be launched here this week.
The test is more reliable than methods currently used to diagnose the disease. Doctors say the genetic test is a step closer to being able to screen all men for prostate cancer in the same way as women are routinely checked for breast and cervical cancer.
At present doctors use a blood test called the prostate specific antigen (PSA) test to check if men are at increased risk of cancer. The PSA test can indicate the presence of a prostate problem, which may sometimes turn out to be prostate cancer. The PSA test gives rise to a large number of false positive results, however. This leads to men having unnecessary biopsies carried out.
The new test, called the PCA3, is being marketed by the American company Gen-Probe and will have the backing of leading cancer experts and campaigners.
It looks for a gene in men’s urine that is produced by prostate cancer cells. If the urine test is positive, this is a more accurate indication that the man has prostate cancer.
Roger Kirby, professor of urology at St George’s hospital, London, said: “Although the PSA test gives us an indication of there being something wrong with the prostate, it does not always tell us if it is malignant. This new test, in combination with an examination of the prostate . . . tells us whether we should advise a biopsy.”
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What you failed to mention in your report was that the NHS will not fund the estimated £200 fee for the test. As is usual in the UK the double standard rers it's ugly head, women are constantly being told to go for their various cancer tests, mone never comes into it. Yet where mens health is concerned the NHS doesn't want to know.
W Ward, Liverpool, England
A high PSA score seems to be the beginning of an unending nightmare for many men and in many cases the test apears to be worse than useless. As is the famous DRE which all men of 50 are supposed to have. Apparently if a DRE finds the cancer it's pretty developed and you're in trouble anyway. The finger can only feel the top of the prostate so it's no better than flicking a coin - heads or tails.
A high PSA - above 4 (?) between 4-10 means you are advised to have a biopsy. Yet it is acknowledged that symptoms of BPH are associated with high PSA and men with prostate cancer can often have a low PSA
Onwards to the biopsy. If you have a high PSA and the biopsy doesn't find prostate cancer this doesn't mean you DON'T have prostate cancer - only that the biopsy needles didn't pick up any samples of prostate cancer - a bit like stabbing through an orange with a needle to find mold. The needle could easily miss something if it is small enough.
I hope this new test ends all this guess work
Pete Kline, Hong Kong, Hong Kong
my husband was given 12mths to live 10 years ago with what was diagnosed as fast growing prostate canser with a psa of 159. we are now ten yrs on the prostate cancer was inoperable with only palative care to offer. he had zoladex injections. a t.u.r.p operation which included an orchadectomy operation which went badly wrong and caused him to go to theatre another 6 times. 20 maximum doses of radiotherapy. he is now on an 8wkly dose of zomeda for his bones and casodex 50mg 1 every other day things are looking a bit better but are we ever going to have any remission its been a long time do we have any chance of remission? his brother also had prostate cancer. is it important for my son now 37 to be checked at any stage i would be happy to find out more. many thanks
veronica wilson, birmingham west midlands, united kingdom
Very interesting! Just by a urine test , without unnecessary
biopsies and their pains!
Michel Chartier, Montréal, canada