Dr Thomas Stuttaford
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Sixty-thousand to 80,000 years ago Ancient Britons leapt up after a night's sleep on what is now the seabed off the coast of Norfolk. Armed with flint axes and spears they were intent on a day's hunting of mammoths and woolly rhinos, activity that couldn't allow any lapse in concentration.
Even as archaeologists were describing the latest haul of wooden, stone and bone implements recovered from the seabed eight miles off the coast of Yarmouth, other scientists were discussing the role of coenzyme Q10 in the work pattern of the British 21st-century worker.
We are proud that we have the longest working day in Europe, but research shows that nature only endows most employees with the physical energy to work for five hours.
Many workers, already tired after a long commute, use every excuse to procrastinate once in the office. A recent survey of 4,000 office workers has shown that few start work before 9.45am and even then their immediate aim is that first cup of coffee. The average number of cups of tea or coffee drunk per head daily in the office is four. Making each of them ensures a rest from the office routine. The average lunchbreak now takes 32 minutes, but when workers return to their desk at 2pm it's time for the graveyard shift. During the early afternoon many office workers are virtually brain dead, fit only to e-mail friends, glance at Facebook or scan eBay. Around 3pm the office leaps to life again. The survey revealed that the average employee wasn't working properly for 151 minutes of every day. The reason for this intermittent work pattern is that most office workers are overtired: 88 per cent also admitted that one day a week their work is undermined by a hangover.
Some biochemists attribute excessive tiredness to the relative failure of the complex system that controls cell metabolism to adapt to, and cope with, the work pattern of today's office worker. Conversely, sociologists interpret much of office tiredness as a symptom of a desire for escapism induced by boredom with the job, or anxieties about mortgages and debt and a lack of job security.
The biochemists were interested in the possible role that coenzyme Q10, also known as coQ10 (ubidecarenone or ubiquinone) might have in providing energy to cope with modern life.
CoQ10 is found in cells but its concentration varies. Advocates of coQ10 have drawn attention to the variations in its levels in the cells, depending on the organ, the age of the patient and the state of his or her health. Levels are greatest in heart cells, other essential organs and the muscles and skin. People suffering from such diseases as Parkinson's, chronic heart failure and neuro muscular diseases have the least of it.
The concept that if coQ10 is associated with degenerative disease it might help to restore or maintain failing energy so that the permanently exhausted could be revitalised has obvious appeal. Most doctors will remember learning about the role of coQ10 as a factor in the oxidative pathway adenosine triphosphate (ATP), upon which all cellular metabolism depends. They accept that its importance in clinical medicine may be underestimated.
The large numbers of patients who tell doctors that coQ10 gives them the energy to face modern life reinforces these thoughts. Others claim that it has helped people with Alzheimer's, atheroma, cardiac failure, Parkinson's and muscular dystrophies. The only answer to this enthusiasm is that coQ10 it is still under-researched and the crucial question - whether the low levels of it found in the aged or diseased are an example of cause or effect - is unanswered.
When discussing coQ10 in supplement form with patients, doctors usually insist that it shouldn't be used in place of any prescribed medicine. Its value is as a supplement. Nor should it be used by a patient taking Warfarin, or suffering from any disease that results in bleeding or bruising. Boots has introduced a new natural form of coQ10 called Kaneka Q10 and from today is offering a seven-day trial pack to those with a lack of energy attributed to low levels of the coenzyme. There is a money-back guarantee if the patient's energy doesn't improve.
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I've taken co-Q10 for a while now to combat the severe fatigue I suffer, caused by multiple sclerosis. It helps me; I'm able to do a full eight hour day in a very busy, stressful job without crashing in the afternoon. Before I tried it, I was usually sleeping at my desk between 2 and 3. And I really mean sleeping, so deeply that my colleagues sometimes had difficulty waking me.
Joon, UK,
I have suffered from ME for 25 years and went through a really bad patch recently when I had a relapse and was bedridden for weeks. A friend suggested Q10. I took 75mg each day for 2 days and felt better then after a few more days the improvement tailed off. I doubled the dose and haven't looked back! It's wonderful stuff!
Menna Kasixka
menna kasicka, Stocksfield - in the NE, UK
I took my first Boots pill at lunchtime yesterday - felt a definite higher energy - but was was awake in the evening more than 2 hours after my normal sleep time; are we sure these pills don't have caffeine or similar in them?
John Campbell, London,
There was a big group of people swarming to take CoQ10 on a forum I was on, as they found it improved their energy levels, made them lose weight, have better skin and had a number of other associated benefits. However, it still did nothing for some people. I think they found 60-90mg to be most effective. I know a study about benefits for cancer patients went over 300mg a day.
Pip, Cambridge,
Simply can't wait to try it!
Patricia Pemberton-James, portsmouth, U.K.
Perhaps you should try this before rushing to spend your money.
http://dcscience.net/?p=223
Voltaire, London, UK
Dr Stuttaford was awarded the Health Food Manufacturer's Association award for Journalist of the Year in 2006, and anyone can see it was well deserved. Bravo!
Patrick Holford, Pillton,
What the article also forgets to mention is that CoQ10 is taken every day by thousands of Danes and Japanese as it known to reverse and prevent gum disease.
drew, london,
There is no reason to have a 9-5 working day in the first place. This routine just dates back to the early days of industrialisation when work outside the home became formalised. Before then most were craftsmen or farmers and worked the hours that they needed to, when they needed to e.g. a tailor would work into the night by candlelight to finish garments in time, while farmers might be up before dawn to look after animals and then have breaks in the middle of the day.
This arbitrary and burdensome obsession with the 9-5 routine doesn't suit everyone. Many I know, especially creatives, get their best work done in the evening or into the small hours of the morning, while others find they work best from 7am. It's all down to the individual so a random imposition of 9-5 routine on all is bound to lead to inefficiencies.
MB, Edinburgh,
Who are you speaking on behalf of when you say "We are proud to have the longest working day in Europe". Not me , that's for sure. It's great to enjoy your work of course, but there are other things in life, such as family, fun, time for reflection etc. Most Brits feel like underpaid worker bees - small wonder we're tired and demotivated.
clare, Devon, England
How will the 'money-back guarantee' work? Are you deserving of your money back if your energy fails to miraculously appear after use of this enzyme? How will you prove it? Did they know you as person buzzing with life and laughter before you became tired all the time? Or were you always a miserable sod lacking a certain vigour for life? So your energy doesn't return due to a massive hangover, poor diet, and prolonged negative thinking on your journey to work on an overcrowded train/bus/road - is it any wonder you feel rubbish throughout the day? So you get your money back. Will the manufacturers actually make a profit on this? Will it actually work on the vast majority of Brits who I suspect are tired all day mainly due to dull weather, too much TV, excessive use of central heating, lack of exercise, negative attitudes, a carbohydrate-laden sugar fuelled diet and dehydration.
Why not try a week of walking, laughing, salads, fruit, water and positive thinking instead?
Victoria , Sydney , Australia
I think Sacha's wallet might be fine if there is a money back guarantee....???
Lucy, London,
Eat your offal, folks. Liver and heart are the richest in this stuff. Liver is also the single most nutritious thing you can eat anyway. It beats the pants off fruit and veg, if you can get over the "toxin" thing. Find yourself some organic liver and you should be alright. But also find a good source of vitamin D or go for sunny holidays in the winter as liver is very rich in vitamin A, and that vitamin is antagonistic with vitamin D, and D deficiency is something you really don't want.
Greg Lorriman, Leatherhead, UK
Sacha's wallet may need a fix after going to Boots
K Urban, London, UK
After a long day in the office, this sounds like just what I need. That's me off to Boots, then...
Sacha, New Cross, UK