Nigel Hawkes, Health Editor
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The doctor at the centre of the MMR vaccine controversy was told by a mother that her child showed signs of autism after receiving the vaccination — and that other parents were facing the same problem, a medical hearing heard yesterday.
Dr Andrew Wakefield. 51, said that he found the story of a link “compelling” and that it “merited attention”. It was his duty as a human being to help mothers who came to him seeking answers, he said.
Dr Wakefield faces being struck off the medical register after publishing in The Lancet in 1998 findings that suggested the triple vaccine could cause inflammatory bowel disease and autism.
Dr Wakefield and Professors John Walker-Smith and Simon Murch are accused of serious professional misconduct relating to investigations undertaken on 12 children between 1996 and 1998. They deny the charges, which run to 32 pages.
He had “absolutely not” abused his position as a doctor in helping this mother, he told the hearing before the General Medical Council in London.
After he published an earlier paper speculating on a possible link between a measles vaccine and inflammatory bowel disease, Dr Wakefield said that he received several calls from parents.
One, referred to as Mrs 2, told him that her child started to show signs of autism and had “terrible bowel problems” after being given the vaccine.
Dr Wakefield said that this “made a great deal of sense” to him as a gastroenterologist because of a well-known link between the gut and the brain. “The story was compelling and certainly merited attention,” he said.
“Mrs 2 said that she was in contact with many parents who had exactly the same experience. Their children had developed chronic bowel problems and autistic regression, often following MMR, but not necessarily, and that they believed the two were linked.”
Dr Wakefield told the GMC that he advised Mrs 2 to ask her GP for a referral to John Walker-Smith at St Bartholomew’s Hospital in London.
Later the child was included in a study conducted by Dr Wakefield. In doing so the GMC alleges that he violated ethical guidelines and acted against the interest of the children.
Asked by his solicitor, Kieran Coonan, QC, if he was in breach of his position at this time, Dr Wakefield said “absolutely not”. He added: “I think if I had not given her that advice, if I had not responded in the way I did, then this panel would have every reason to have me before it. It was my duty as a physician and as a human being to respond to the plight of this mother, and, if I could, point her in the direction of someone who could help her, that was my absolute obligation.”
The three doctors had developed a hypothesis linking MMR and autism and decided to conduct clinical studies to test it, the GMC was told.
The hearing continues today.
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Is it of no interest to the anti-Wakefields that not one parent of a achild with GI issues or autism or the combination of the two has come forth to complain about him, even anonymously? The evidence in the Lancet paper has never been refuted so far as I know; the Lancet backtracked on the conclusion, but the science is sound, and I happen to think the Lancet should be held every bit as responsible as the men who submitted it, if it's research that people want to pillory. But why pillory this honorable man-- he came all the way back to be heard, when he and his loyal family live in the US now, and it hardly matters if he's "struck" from the register. I doubt his intention is ever to practice medicine in the UK again-- I certainly wouldn't were I in his shoes. It has changed how I feel about England, and all I thought she stood for.
Anne Van Rensselaer, New York, NY
Somebody put a muzzle on this man. He does more harm by continuing the myth that the shots are responsible for autism. He doesn't convince any sentient person who has read the research, just the general public who continue to parrot his nonsense!
To the poster whose child has stomach issues....take him to an internist and get a proper DX. Anybody who is telling you 'that's just autism' is a Quack!!
Kelly, Orlando, Florida, USA
MMR is not the cause and there is no cure for autism, it's a neurological disorder, and all you can do for it is train a person with autism to display more acceptable behaviors!, but for who I ask myself. I truly feel we should allow these children to develop in their own way and in their own time..
Understanding really is essential to embracing these unique individuals with autism, we may be different, but at least understand me before trying to change me.
"The measles, mumps and rubella vaccine is safe and does not cause autism, the most comprehensive study carried out on the jab has concluded. To think there are people out there who seriously thinks it does? worries me. Maybe they want to climate me from this world I am on the autism spectrum.
Need more info - Vaccine and Autism:
http://asplanet.info/forum/index.php?topic=43.0"
Why can not people except the fact that people on the autism spectrum are just different, wired differently and always will be. www.asplanet.info
Alyson Bradley, Christchurch, NZ
I support Dr. Wakefield 100%, as should any other caring doctor. Our autistic kids present gastrointestinal disorders that go ignored by Mainstream Pediatricians.
We go to them and tell them our children writhe in pain, have extremely loose bowel movements up to 15 times a day and we are told, that is autism - go home a deal with it.
Comments regarding "no proof" are insulting to us parents who have seen what Dr. Wakefield has done to resolve serious ilness in kids in the U.S. The world needs more Andy Wakefields, more doctors who will not bow to pressure from those who want to this all to go away.
I suspect there are many doctors that would love to help our kids but silently say to themselves "I don't want to become another Wakefield". Because of the GMC scare tactics, our kids go without the necessary care. The GMC should be ashamed and they should be the ones on trial here.
Tim Kasemodel, Wayzata, Minnesota, USA
This case is to do with professional conduct and research ethics. We shall just have to wait and see if Wakefield is guilty of misconduct. We already know he isn't correct about the science (many subsequent studies have shown this, as well as the fact that his research co-authors have disowned his research findings).
Jordan, Manchester, UK
Doesn't this just look the the Inquistion, sorry, Congregation for the Doctrine of the Faith?
There was also a fine piece that Robert F. Kennedy Jnr wrote for Rolling Stone in July 2005. It described a pharma conference in the the US, where the participants were not even allowed to take notes, let alone record proceedings. The sole item on the agenda was: We know that thiomersal causes autism, how do we cover this up?
Malcolm, Chicago, IL
About time that someone spoke up about the misdeeds of the pharmaceutical corporations.
Thiomersal - organic mercury used as a preservative in vaccines etc - is very toxic by inhalation, ingestion, and in contact with skin (EC hazard symbol T+), with danger of cumulative effects. It is also very toxic to aquatic organisms, and may cause long-term adverse effects in aquatic environments (EC hazard symbol N).[7] In the body, it is metabolized or degraded to ethylmercury (C2H5Hg+) and thiosalicylate which is even more toxic.
The low cost of Thiomersals use has meant that its continued inclusion is assured - no matter what the health cost !
Martin Downs, Oxford, Oxfordshire
Thank you Nigel Hawkes for your fine article.
It is a breath of fresh air when one reads a good account by a health editor. I was present at yesterdays hearing at the GMC and it was a pleasure to be supporting the good doctors Wakefield and co. It was magic meeting up with all the other parents and supporters and I believe in my heart that these brave men will be cleared of any wrong doing and hopefully the vaccine damaged children will be helped now and in the future by other doctors wanting to know the truth about un-safe vaccines.
Joan Campbell, Glasgow, Scotland
I hope that Wakefield et al's inquisitors at their hearing are aware of how time has moved on since their study of 1998, and they have been vindicated by independent research. One such study, by V.K. Singh, PhD, Research Associate Professor of Neuroimmunology in the Dept of Biology at Utah State University, as reported to the US Institute of Medicine (IOM) in Feb. 2004, discovered that (1) autistic children harbour abnormal vaccine serology (MMR antibody levels were higher in autistic children as compared to controls), and (2) there was a correlation between this vaccine serology and brain autoimmune antibodies (marked by Myelin Basic Protein (MBP) antibodies; which is a contaminant of the MMR jab from the chick embryo cells it is cultured on). His conclusion: the study "suggested a causal link of measles virus with autoimmunity in autism." Thus Wakefield et al have been supported in their findings. This should take precedence over any feeble charges about Wakefield's integrity.
Stan Stanfield, Forres, UK
I believe Dr. Wakefield to be a hero to care enough to go through all he and his family has to treat and try to protect children, we in the US are lucky to have such an ethical doctor on our side thank you Andy for all you do!
kimberly Linderman, galesburg, usa Illinois