David Rose, Health Correspondent
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Women who take a statin can reduce their risk of having a heart attack or stroke by nearly 50 per cent, even if they do not have unhealthy cholesterol levels, research suggests.
A daily dose of Crestor (rosuvastatin) reduced the chances of subsequent cardiovascular events by 46 per cent compared with those who took a placebo.
The trial involved almost 18,000 people — one in seven of them from Britain. Initial findings that showed an overall benefit for men and women who took the drug were published last year.
The latest analysis, focusing on the effects for women, were presented to the meeting of the American Heart Association in Orlando, Florida.
More than six million people are prescribed statins to lower their cholesterol levels, but at present the drugs are given only to those at significant risk of a heart attack or stroke.
All the women involved in the trial were over 60 years of age and did not have high cholesterol. They each had high levels of a protein called hsCRP — high sensitivity C-reactive protein — which is linked to inflammation in the arteries.
Sarah Jarvis, a GP in London and the Royal College of General Practitioners’ spokeswoman for women’s health, said: “Cardiovascular disease can be mistaken as an ‘old man’s’ disease, while unfortunately the evidence suggests that people are suffering cardiovascular events younger and more women are at risk of developing the disease.
“There has long been support for the wider use of statins in women but we didn’t have the outcomes data to support these recommendations. This data is extremely exciting.”
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