The Colony Club in Soho has been a watering hole for hard-drinking creative types since it was founded by Muriel Belcher in the late 1940s. It is a reasonable bet that her confidants - Francis Bacon, Lucian Freud, Jeffrey and Bruce Bernard, Michael Andrews, Eduardo Paolozzi and other regulars from the art and entertainment world - would have had high IQs. Some members may have been nightmare clients for their bank managers, exasperating husbands, wives or lovers, but no one would doubt their talents, originality and intellectual ability.

Research has now shown a link between high childhood IQ and an adult enthusiasm for alcohol that leads in some cases to problem drinking.

Parents may be aware that the easiest children to have around the house, and those who are also the most likely to have a predictable, comfortable lifestyle when adults, are those with a slightly aboveaverage intelligence, neither too clever, nor stupid.

Most parents would be proud to be told by a teacher that their child has a higher IQ than his or her peers. It would not occur to anybody that there might be an association between that high IQ at the age of 10 and an enthusiasm for the drinking culture, leading occasionally to a problematic excessive alcohol intake.

This association is even stronger among women than among men. Research by Dr G. David Batty and colleagues at the University of Glasgow, published in the American Journal of Public Health, compared the mental ability scores of 8,170 British boys and girls at the age of 10 with their alcohol intake and any alcohol problems when they were 30.

Whereas most of the clever children grew up to drink as most people do, reasonably and moderately, the likelihood of developing a drinking problem if one were unusually bright increased 1.38 times in women and 1.17 times in men.

Could this account for the importance of Oxford wine cellars in college life and, possibly, the tendency of intelligent heavy drinkers to start the habit while at university?

As most of us begin to look forward to and prepare for a convivial Christmas, it is as well to review thinking on alcohol. Nobody denies that excessive or binge drinking presents a danger to the drinker and those around them, but modest drinking is still life-preserving rather than life-limiting.

More women than ever are drinking to excess, and it is hard to know who will suffer liver damage and what level of alcohol consumption is liable to cause it. Nor can anyone condone Friday or Saturday night binge drinking. This represents a hazard to a young drinker's liver, even if most get away with it. It is also true that problem drinking by clubbers causes a considerable nuisance in the neighbourhood and contributes to petty crime.

The evidence that alcohol is a possible cause of breast cancer in women is now accepted, as alcohol increases the level of oestrogen and this is known to be carcinogenic. However, women can comfort themselves as they enjoy a glass of wine at Christmas that, statistically, those who drink in moderation are likely to live rather longer than their teetotal contemporaries.

Only 6 per cent of women and 8 per cent of men drink at what even the strict Department of Health considers a hazardous level. For the other 90 per cent-plus of the population, moderate drinkers as well as teetotallers, alcohol doesn't represent a health problem. Moderate drinkers even have a small but significant advantage over the teetotallers in the longevity stakes.

A surprising statistic is that, in the majority of the population, damaging patterns of drinking are falling. However, alcohol-related hospital admissions still show an increase. This may be because more medical conditions are now included under this category, and because more women are now drinking more than 20 years ago.

Although many common forms of heart disease are less likely in moderate drinkers, there is one adverse effect of alcohol on the heart. Up to 10 per cent of patients over 75 suffer from atrial fibrillation, an irregularity of the heart's rhythm. In 45 per cent of the cases in which a patient has suffered the most common form of stroke, it has been preceded by atrial fibrillation.

Recent research, reviewed this month in the British Journal of Cardiology, suggests a strong association between atrial fibrillation and alcohol intake.