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YESTERDAY’S paper is today’s fish and chip wrapping, so the news it contained
is soon forgotten. This may be just as well for those who figure in the
gossip columns or in the Sunday papers, but it is a dangerous principle when
medical news stories are involved.
In spring this year there was a scare, a thoroughly justified one about the
spread of avian flu, better known to most people as bird flu. For a time
people worried about their Far Eastern holidays, and wondered whether they
should cancel their bookings and brave Benidorm instead. The scare was soon
superseded by other worries, and the holidaymakers who were so concerned in
February and March will now be sunning themselves at a newly refashioned
Thai beach complex, just as they did last year.
So thoroughly had the hazard that avian flu presented to the world been
relegated to the margins of the news that a warning by the World Health
Organisation last month was largely overlooked. Their experts advised that
the strain of avian flu that caused such alarm earlier in the year has now
shown changes in the H5N1 influenza virus, which is likely to make it more
infectious to humans. They also reported that there had been more outbreaks
of avian flu, and that these outbreaks were lasting longer than had
previously been noted. Furthermore, blood tests on the people who have been
in contact with avian flu showed that there was an increasing number who
demonstrated a response indicating that they had suffered a sub-clinical
infection.
The good news, or comparatively good news, from WHO was that the death rate
among those infected with avian flu recently was not quite as high as it had
been previously. The age range of people who had more recently caught flu
from their hens, ducks, or migrating water birds was also much greater. The
earlier outbreaks had attacked mainly young active workers rather than the
elderly, infirm and children who usually suffer in any epidemic. As long as
the virus is spread only from chicken to chicken, or even chicken to human,
and not human to human, chicken-house workers would be at greater risk than
those such as the elderly or the under-fives, who have a poor immune system.
It was noteworthy that this pattern was changing.
There is as yet no firm evidence that the dreaded human-to-human transmision
of avian flu is anything other than an extreme rarity. However, since the
publication of the WHO report, there has been news of the spread of avian
flu in Indonesia, where three cases have been reported. The WHO researchers
said that, although it couldn’t be proved that human-to- human transmission
was occurring, there were some signs during the spring outbreaks that it was
possible that some of these cases could have been spread in a way that
suggested this was happening.
There is a possibility, some doctors think even a probability, that, once the
H5N1 strain has mutated so that it is able to spread from person to person,
it will not be as lethal as the infection when caught from a chicken or
duck. They predict that the death rate from it might then fall to about 30
per cent. This is considerably lower than the current mortality rate, but is
not a statistic that is likely to be reassuring to the general public.
Although the only publication to give the WHO warning much coverage was GP
magazine, the Government has now issued a statement about its plans for the
introduction of a vaccine against avian flu. Only enough doses will be
stockpiled for essential medical and other services. Doubt has been
expressed that this vaccine will be able to trigger a sufficiently strong
antibody response to prevent an attack of the flu in most people.
The vaccination may therefore be of little help to the community, for, if
doctors and nurses were only partially protected, it may well be that the
mild flu they would suffer would be worse than them having a normal attack.
It would be a great advantage for those who had the vaccine in that
presumably they would have a better opportunity of recovering but if their
illness was so mild that they were able to continue working while suffering
a modified attack they might spread the flu even faster, and to people whose
resistance was already at a low ebb by reason of their age or other
diseases.
The only way that a pandemic as widespread, but much more deadly, than the
Spanish flu of 1918-19 can be avoided or nullified is either to produce a
stockpile of enough of the present vaccine for everyone, or preferably to
manufacture a more effective one so that total protection will be afforded
by it. In the meantime, the Government should be stockpiling vast amounts of
Tamiflu so that if the worst happens, and experts think that this is
inevitable, there will be enough of the anti-viral agent to treat the 30 per
cent of the population who are predicted to catch flu if there is an
epidemic.
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