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Gordon Brown said today that Labour MPs could vote with their consciences on three sensitive elements of his controversial embryo research plans, in an attempt to stave off a potential rebellion.
The Prime Minister continued to refuse MPs a free vote on the Human Fertilisation and Embryology Bill, saying that they would have to vote with the Government when it has its second and third readings in the House of Commons.
However – amid concern that the Government faced a significant revolt from Roman Catholic MPs – Mr Brown pledged a free vote when individual sections, or amendments, of the Bill are cherry-picked and debated between the two readings.
MPs would be allowed to vote with their consciences on amendments dealing with three particularly sensitive areas, those dealing with IVF research, saviour siblings and mixing embryos, he said.
Mr Brown added that he would continue to urge MPs to support the legislation in its entirity, saying that he was writing to every MP in the party to explain why he backed it.
Today's move comes after a weekend of agonising by the Prime Minister amid fears that three Catholic Cabinet ministers, Ruth Kelly, Des Browne and Paul Murphy, and backbench MPs could vote against the Government.
The Catholic Church this afternoon said that Mr Brown's acknowledgement of MPs' consciences was "better late than never" but added that the Bill still contained some "deeply troubling proposals".
In addition, at least one Catholic Labour MP said she would still rebel throughout the Bill's House of Commons stages unless aspects of the legislation are changed.
Scientists welcomed the decision to give MPs a free vote, saying that they hoped that it would end the politicisation of a scientific discussion.
Dr Stephen Minger, Director of the Stem Cell Biology Laboratory at King’s College London, and one of the scientists who hopes to carry out research using the "admixed" embryos, said: "I think one thing we have proved over the past year is that the scientists who want to do research on human admixed embryos are prepared to spend huge amounts of our time explaining to the public and policy makers why we want to do this and exactly what is involved.
"I welcome any opportunity to debate this further and I hope that Gordon Brown’s announcement today will put an end to the political point scoring and move the debate back to the science and ethics of this research."
Professor Colin Blakemore, former head of the Medical Research Council, said: "I hope that this decision to allow a free vote will take some of the heat out of this issue. However, this makes it even more important that MPs should be fully and accurately informed about the science underpinning the Bill.

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Strong arguments against aspects of this bill are provided by the book Embryo: In Defense of Human Life, co-authored by Princeton expert on Natural Law, Robert P. George, who bases his argument on science, philosophy, natural law, and universal ethics, not on religious grounds. This was pointed out on the BBC discussion of the subject where the defender of the bill was not willing to identify any limits that science would agree to in this area.
Richard L.A. Schaefer, Dubuque, Iowa/USA
It was Edmund Burke who set forth the principle, right after his election, that he would vote according to his own judgment and not always according to the people's views. To do otherwise would be to adopt the Nazi principle formulated by Eichmann of simply following orders, not conscience, or else the requirement to sometimes vote with the mob.
Richard L.A. Schaefer, Dubuque, Iowa/USA
Looking at the Cardinals' Talibanistic attitude it is no wonder that the Muslims are asking for Shari. All other religious group will ask for their own laws, and it is disgraceful that Brown has yielded to religious nutters.
Simon, Manchester, UK
So the MPs were allowed to vote with their conscience on this issue, but were denied this right when it came to the EU and the Treaty. Nick Pryor, London, England said it all "Our MPs are the elected representatives of their respective constituencies. They should vote according to the will of the people who elected them," So if not voting with their consciences then it should at least be according to the will of the voters. Why all the double standards with Gordon Brown?
Douglas Cochrane, Halifax,
Since when was the Church entitled to dictate how MPs should vote? Or (to put it another way) why do MPs seem to think that they entitled to vote solely by reference to their own personal convictions?
Our MPs are the elected representatives of their respective constituencies. They should vote according to the will of the people who elected them, based upon informed reflection of the merits of the legislation before them. If the majority of the people represented by an MP would favour the legislation, the MP has a moral imperative to support the Bill, notwithstanding any personal reservations.
It appears the Church is trying to assert a moral veto over parliamentary decision-making by appealing to individual MPs' personal convictions. If so, we have more to fear than the moral implications of this isolated piece of legislation.
Is this the thin end of the wedge? Are we witnessing the erosion of the church/state divide that has already run wild in the States? God forbid...
Nick Pryor, London, England
So Gordon Brown won't insisit on a 3 line whip for the bill allowing all to vote with their concience?
But this only allows the catholics to insisit on their own "3 line whip" for their views, disturbing the state's process and once again ensuring the baseless beliefs of the vatican rule over society's democratically elected chambers.
If we accept that the catholic MPs vote for the catholic point of view and not their party line, then we might as well give up and have a catholic state. Or why not a Muslim state? Or any other religion?
Matt, Antibes, France
Weak man! Should have shown courage by standing up to the Catholic brigade who kept silent when their clergy abused children for decades. These religiou brigade will come for more having tasted the blood. Cameron should be ashmed for not standing up for research which every one believes except those who still argue that the Earth is flat and Gelileo was a nutter.
Rob, Brighton,
I am sorry for putting it so strongly, but the fact that people are still questioning the "humanity" or otherwise of the human embryo is so bizarre that one struggles to understand the mind that could contain such idiocy.
Jerome Lejean, the famous French physicist who discovered the cause of Down's Syndrome, once gave evidence to the US Senate and during it, said: "If an embryo at the MOMENT OF CONCEPTION is not a human being, it will never turn into a human being. Conversely, an embryo at the MOMENT OF CONCEPTION can ONLY become a human being, not anything else. Ipso facto, an embryo at the MOMENT OF CONCEPTION can ONLY be a human being".
Why are people so very blind? Is it that decades of abortion have effectively sold you all the lie that an embryo is not a human being?
A lie that means a government can now tell us that we are only human beings ONLY WHEN the law says we are! What madness, what political obscurantism in the service of utter moral degradation this is!
Benedict Carter, Moscow, Russia
I'm disgusted - though sadly unsurprised - by the church's efforts to prevent research that will help humanity: morally bankrupt as ever.
Hugh, London,