Sarah-Kate Templeton Health Editor
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TWO married couples have undergone Britain’s first kidney swap operation after legislation allowed people to donate organs to strangers.
One person from each couple needed a kidney but could not receive it from their spouse because their organs were not a suitable match.
Neither knew the other couple but were matched anonymously by doctors who carried out simultaneous operations to transfer the healthy kidneys to each of the sick people. It is believed each couple is still in the dark over the identity of the donor from whom they received the organ that could now save their lives.
The swap was made possible by the Human Tissue Act. Until it came into force in September last year living donors were only allowed to give kidneys to those who were genetically or emotionally related, such as a husband to a wife.
It was also disclosed this weekend that doctors had conducted the first British “good Samaritan” operation in which a donor gave up one of her healthy kidneys to be transplanted into a stranger who had suffered renal failure.
Unlike the swap in which the married couples each gave a kidney to strangers in order to receive a better matched organ in return, the good Samaritan donor gained nothing from the surgery other than fulfilling her desire to help others.
The good Samaritan donation was also made possible under the Human Tissue Act. There should be no impact on the donor’s health, though there is a slight chance she could need dialysis and a transplant if her remaining kidney fails.
The operations have been welcomed by UK Transplant, the National Health Service body responsible for allocating organs. Maxine Walter, acting director of communications, said: “This is a milestone. Legislation was changed in order to create opportunities for these new types of transplants and we are pleased to see that lives are being saved as a result.”
The Human Tissue Authority, a separate agency that regulates transplants, has so far declined to give details of how successful the kidney swap and the good Samaritan donation have been.
There are more than 6,400 people waiting for a kidney in Britain. Every year about 400 patients die waiting for a donated organ. Before the new legislation the patients who took part in the kidney swap would have had to wait on the list for an organ from a dead donor to become available.
Supporters of the swaps say they are a practical way of tackling the organ shortage but critics see the operations as the start of a slippery slope towards bartering for body parts.
Sue Roff, a senior research fellow at Dundee University Medical School and an expert in the ethics of organ donation, backs kidney swaps and good Samaritan donations but said others regarded them as a step towards a trade in organs.
“If there are two people with kidney disease and relatives with kidneys they wish to donate on their behalf but medically this is not possible, it is common sense to organise what you might calla barter,” said Roff. “But we have been cautious about this because of the ‘slippery slope’ principle. People fear the next step would be an organ market.”
There are also fears that a spouse or relative may be put under pressure to donate a kidney so that their loved one receives an organ in return.
As well as leaving themselves with only one kidney, a donor has a 1 in 3,000 chance of dying from the operation and runs a 2%-4% risk of suffering complications from the surgery.
In addition to understanding the risks good Samaritan donors need to go through extensive psychological testing to ensure they have the right motivation.
Margaret Challinor, a teacher from Manchester, is preparing to become a good Samaritan donor. Challinor, 62, who has chosen to be identified by her middle name to avoid too much publicity, said: “I have had a healthy, lucky life.I have had no diseases. It suddenly occurred to me that my children are grown up and healthy and I thought, ‘Why not do this?’ It would be good to save a life.”
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It is great news that we have had our first kidney swap in the uk. But why are we not doing more. I am a very healthy 51 year old male and my wife requires a kidney, Sadly I am not a match however I would glady go on any swap register. Is it money thats holding back the NHS From doing more?
Andy Mullen, Aberdeen , Scotland
I would gladly of given one of my kidneys to a stranger if another stranger had then given one of their kidneys to my husband - a living stranger. I did donate one of my kidneys to my husband - Thank God that we were compatible, but if we had not been I see no wrong in doing a three way swap - we all benefit - this must be encouraged. There are many people with kidney failure who would have a much better quality of life with a new kidney - this must be encouraged - and applauded. There are not enough dead donors available and thousands will spend their lives on dialysis if more Living Donors are not found - please don't put donors off - it is a truly wonderful thing to be able to do,
Lynda Gammons, Spalding, Lincs
Goldie - I have to say that I find your views offensive. At present people only donate kidneys purely for altrusitic motives and are thoroughly examined and tested to ensure that they are not unnecessarily putting their lives at risk. I am sorry that you cannot understand it, but it is a truly remarkable gift.
Also not all renal failure is inherited and in many cases it is only through several generations being diagnosed that it is picked up so don't be too quick to judge.
Lastly despite your hereditary condition you are clearly not yet on dialysis (and I would never wish it on anyone) but the fact is that whilst a transplant does save money it also gives a far better quality of life to the recipient, and studies have determined that most donors live longer than average (probably because only very healthy people are allowed to donate).
There are few people, eligible for transplant, who would not choose that over dialysis any day - I know, I have been waiting for nearly 6 yea
Mandy, London,
"Cannibalism?" I wondered if Goldie from Manchester is aware that you don't eat the kidney. They put it in surgically! How sad and uneducated a view point to think that it would be "using" someone to allow a loved one to "give up" a kidney for another. Whether after brain stem death, after cardiac death or in this case of choosing to living donate a kidney, it is a truly autruistic act to donate an organ to save another person's life. Would more people be willing to donate organs for transplant, blood, and cord blood after delivering a baby, there would be a few less senseless deaths in this world.
Sarah, London, England
Well done to the good samaritans! As long as people choose to make these donations without any pressures, this is an excellent way to help others. They must be very special and brave people to do this.
Alison, Leeds, UK
God, this is even worse than the call for everytone to be an organ donor when they die. Now you don't even have to be dead before your organs are ripped out of you. can't wait for the crazed pressure groups to crawl out of the sewers and start guilt tripping all people who choose to hold on to their organs
phollie, Bromley, UK
No one of humility would allow another living person to have a kidney removed and donated to them. No one would allow someone they loved to give up a kidney for them or anyone else. This is because they would be using them.
It is not a good thing to use people in this way at all. Those who are willing to be used for their body matter are being taken full advantage of by those who claim to love them. The system conspires in this, fascilitates it and profits from it. Dialysis is more costly than transplants unfortunately and this corrupts people.
It is worth considering that immigration trends have increased renal case loads in the western world. Also that renal failure can be inherited and so the most unselfish thing to do is dont reproduce if you have such genetic conditions.
I have a heritable condition and I would never reproduce. Nor would I ever allow another living person to forfit body materials such as kidneys to me. I'd consider this canibalism.
goldie, manchester, uk