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Women who go through the menopause have nearly double the risk of suffering respiratory diseases such as asthma, but could protect themselves by taking HRT, research suggests.
Rates of asthma were found to nearly double in menopausal women compared with normally menstruating women, an effect attributed to falling oestrogen levels during and after the menopause.
The studies, presented yesterday to the annual Congress of the European Respiratory Society in Stockholm, are the first to show that the hormone has an important role to play in lung protection and repair.
Problems with breathing and reduced lung function were particularly pronounced for those women who were very thin or overweight.
Although the exact protective role of oestrogen is not yet known, the findings suggest that women who take hormone replacement therapy (HRT) may avoid some of the problems.
Francisco Gomez Real from the University of Bergen, Norway, who led the research, said: “Women who have not menstruated in more than six months have more respiratory symptoms and lower lung function.” This can be explained by the fact that although oestrogen is reduced in all women following menopause, thinner women have the lowest amounts.
At the menopause, the fat cells become the primary source of oestrogen, and women who have more fat cells have higher levels of the hormone, which seem to protect the lungs.
In very overweight women however, other factors come into play. Larger women are known to be at greater risk of cardiovascular diseases and diabetes. Asthma and lung function are also reportedly worse in these women and so the high levels of the protective oestrogen are less relevant.
“What is important now is that menopausal women are told by their doctors that they are at risk of deteriorating lung health,” Dr Gomez Real said.
The study, which is expected to be published in the Journal of Allergy and Clinical Immunology, involved more than 1,300 menopausal women aged between 45 and 55 from nine European countries and America.
The women completed a questionnaire about their respiratory health and menstrual cycle and received practical assessments of their lung functions, including spirometric testing, which measures lung capacity. A total of 21 per cent were taking HRT.
Previous research, involving a larger proportion of older women, nearly half of whom who were taking HRT, has suggested that menopause actually reduced asthma.
The findings suggest that the therapy could cancel out potential respiratory problems caused by less oestrogen, Dr Gomez Real said.
He said that the latest findings were “just the beginning of the research”, and recommended that women take more care of watching their weight, and sticking to “an optimum weight with a body mass inded of 25.”

Exposure to pesticides may lead to asthma in farmers, research suggests. A study presented at the European Respiratory Society Annual Congress in Sweden showed that more than 16 insecticides, fungicides and herbicides, many in common use, are strongly linked to an increase in asthma. Six products have already been removed from the market, but nine others, including captan, diazinon and coumaphos are still widely used. Coumaphos, a fungicide, was found to have the greatest association with asthma, which affects more than 5 million people in the UK.
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Reply to Sue Garman
Hi Sue,
I'm 41 from Manchester - I developed Asthma last year and have had 3 really bad attacks, the last one - staying in hospital for 6 days!!!! Even after the hospital stay and various visits to a chest consultant I'm none the wiser and very frustrated. I'd be really interested in hearing more about your story.
Alison, Manchester, England
If youhave endometriosis (particualrly throughout your body, including the lungs), your Asthma DOES become worse.
I cured myself of exceptionally bad Endo/m by visiting a homeopath, taking homeopathic drops for 15 months and sticking to the eating regime she gave me, also for 15 months. It was NOT pleasant! BUT, 18 years later I still am allergy free, don't have asthma, am slim and, having just turned 60, am healthier than the average 35 year old.
My suggestion? Try the original medicine first (yes, I know the current medical profession calls it alternative, but 'the alternatives' have been around for several hundred years. Modern medicine for only 120 years!) Keep looking until you find what's right for you.
penny whiteley, Sydney, Australia
I have Endometriosis (Endo) which starts by developing through out the reproductive area & spreads through out the body like cancer. Now having Endo on the arm(s) & lungs being a rare case. Endo entereacts with the immune system & causes or makes allergys worse. Endo can be contribute with menopause also. I wonder if this can cause asthma as well? I have trouble breathing. I have Endo through out my whole body. And I was beginning to wonder if I developed asthma because of all of this. I have on mysite how to get ahold of the Endometriosis Association if anyone has any questions. Its listed under: karenlorraine
Thank u,
Karen Johnson
Karen Johnson, Bristow , Oklahoma Unites states
I thought asthma worsened on HRT.
Jill, Barnet, UK
I'm 43 year old woman and am experiencing terrible asthma symptoms and there is a definate pattern with my periods, so I take the pill to stop bleeding. I am very depressed as I have put on weight. My asthma is so bad I feel I cant go on. Just started a new inhaler called symbicort. I'll see what happens.
Sue Garman, East Preston, ENGLAND
I have Endometriosis (Endo) which starts by developing through out the reproductive area & spreads through out the body like cancer. Now having Endo on the arm(s) & lungs being a rare case. Endo entereacts with the immune system & causes or makes allergys worse. Endo can be contribute with menopause also. I wonder if this can cause asthma as well? I have trouble breathing. I have Endo through out my whole body. And I was beginning to wonder if I developed asthma because of all of this. I have on mysite how to get ahold of the Endometriosis Association if anyone has any questions. Its listed under: karenlorraine
Thank u,
Karen Johnson
Karen Johnson, Bristow , Oklahoma Unites states