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The makers of Prozac have launched their first ever antidepressant for dogs, a once-a-day chewable tablet flavoured with beef.
The product, known as Reconcile, received approval from the Federal Drugs Administration in the United States today for use on dogs suffering from separation anxiety from being left alone for long periods.
Like Prozac, Reconcile is a selective serotonin reuptake inhibitor. The drugs should be used in conjunction with therapy to modify the dog's behaviour, the FDA said. It can be taken by puppies as young as six months.
Eli Lilly, which makes the new drug, says that more than 10 million US dogs exhibit strange symptoms from being left alone too long.
"Lilly research shows that 10.7 million, or up to 17 per cent, of US dogs suffer from separation anxiety," said Steve Connell, Lilly's manager of consumer services for companion animal health.
"We're thrilled that our first product for dogs can help restore the human-pet bond."
He said that in field studies of around 600 dogs, 73 per cent of dogs taking Reconcile and undergoing therapy showed better behaviour within eight weeks, compared to dogs receiving therapy alone.
In Britain, research among pet-owners carried out for Sainsbury's Bank in 2003 indicated that 632,000 dogs and cats had suffered from depression in the previous year.
Nearly three times as many pets had suffered from behavioural problems that which could be linked to depression, often resulting in the animal damaging its home or becoming moody or aggressive, according to the research.
Symptoms included attacking furniture, reported by an estimated 1.86 million owners; moodiness, suffered by 1.8 million cats and dogs; loss of appetite linked to stress or emotional problems, 922,000; and incontinence, reported to affect an estimated 803,000 pets.
"People are leading more stressful lives and unfortunately this can have an adverse effect on the health of our pets," said Clare Moyles, Sainsbury's pet insurance manager.
"Cats and dogs can be very susceptible to their owner's feelings and if they sense that they are unhappy they can become agitated and depressed."
Market research company TNS interviewed 1,002 people in the UK in December 2003.
Eli Lilly warned however that Reconcile had shown side effects in a small minority of dogs, including anorexia, vomiting, diarrhoea, barking and fits.

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I gave my dog one pill of Reconcile and he had such a bad reaction to it that he may of had a stroke. I am waiting to hear the results of his MRI.
Jess, Huntington, NY, USa
For anyone who's lived with a dog who has Post Traumatic Stress Syndrome from an early history of abuse, medication can be a life-saver, both for dog and person. I have an 11-year old Golden/Chow mix who was abused for the first 5 years of her life and was, according to a behaviorist I consulted recently, "unadoptable". Yet, I took her in as company for my other dog and she has been a challenge. After almost 5 years together, she still startles at the slightest sound, runs from me crying in the house and generally is a nervous wreck. I have a quiet household and I take her for long walks and runs in the woods. None of this makes a difference. In fact, when she's tired the crying/whining is worse. I have tried aromatherapy, T-touch, an animal communicator/healer, massage,pheramone therapy . None of this helped very much . I completely understand someone saying medication is an alternative to euthanasia!
Darlene, Greenfiel, MA
M. Salamone in NY "I will continue to use it along with training rather than put him down." What?!! That's your only other alternative? How about finding the dog a better home... I'm sure you are a caring owner (obviously making much effort) but it sounds like the dog is highstrung (which is actually par for this mix breed). This dog would in fact benefit from living in a rural environment, but also with a lot more daily one-on-one attention and exercise. Wear the dog out with exercise and play time (and use the items he is leary of in play; like, chase the mop head, keeping handle short and low to floor) and he won't have the energy to spaze out.
And Duncan in England, wow, a little overboard there... they said they are using the drugs to facilitate training, not a be all end all. Now I'm not one for medicating (people or animals), and the Pharmaceutical companies are out of control, but sometimes it's a necessary evil, if you will, to a better end.
L. Saviour; Portland
Lee Saviour, Portland, OR
In 2000, I adopted a 4 yr. old mixed breed dog (golden retriever, border collie +). His life is based on terror. He is afraid of children, loud noises, buses, trucks, loud voices, adults, other dogs. He is intensely overprotective and territorial. At first, he did not respond to my voice unless it was a command, I could not approach him holding paper or a towel or a broom or mop. He belonged in puppyhood to a crack adict who was evicted from his apartment. His next owner died after two years. I have trained him, consulted a behaviorist, used dog whisperer principles and Amechian bonding. Everything helped but not enough. He would do well in a quiet neighborhood. I live in a dangerously high traffic area in New York City. He has been on prozac for 3 weeks. Is it a cure-all? No, but it is helping. I will continue to use it along with training rather than put him down.
M. Salamone, New York City, USA
I think it is an absolute disgrace that people are resorting to drugs for emotional problems in their dogs.
The problem is not with the dogs. It is with the humans. Dogs dont speak our language we need to learn theirs.
For all you people that think this cant be done, I can tell you yes it can be and it really is so simple to learn and you dont need drugs to do it.
I practice a method called amechian bonding. I have used this method of communicating with dogs over and over. I do volunteer work in a number of refuges in Perth Australia and this method provided success after success with each and every dog I have ever worked with. I have had success with at least 50 or more dogs with a variety of different problems including separation anxiety, agression, timidness, dogs who jump all over you, biters you name it. All dogs respond to this method of communication.
This site will give you more information:
http://www.janfennellthedoglistener.com. Do your dog a favour.
Lisa Hollands, Perth, Australia
Prozac for dogs is no worse an idea than Prozac for humans (which of course leaves it open for discussion!), as long as it is used responsibly and correctly, by appropriately experienced veterinary surgeons, as part of a behavioural modification programme where adequate resolution of the dog's unwanted behaviour cannot be achieved by appropriately skilled behavioural modification alone. Thus, in the vast majority of cases it will be unnecessary, but that is no reason to ban it from use in the few cases where it will improve the welfare of the individual dog. (Once again, this compares closely with human use.) Human formulations of fluoxetine have always been available to UK vets for "off-label" use in dogs, and have occasionally been prescribed with varying success; also other different neurotropic drugs for dogs are already licensed for veterinary prescription in the UK, and have been in use for many years. Prozac will be extensively tested for safety before any UK licence is granted.
Duncan, London, England
As someone who's has to deal with the effects of clinical depression at very close quarters, I find ignorant attitudes like those shown by Edmund Dantes from Connecticut deeply insulting.
Sufferers from clinical depression are not experiencing "normal emotions". They have a massively debilitating condition which affects every aspect of their day-to-day lives. It is a genuine medical condition which can be corrected by a variety of treatments, including in some cases the prescription of drugs to resolve measurable chemical imbalances.
The problem we have is that ill-informed people like Mr Dantes see the word 'depression' and immediately equate it to 'just feeling a bit low'. "Cheer up," they say. If only it was that simple - it's like telling a cancer patient to just "get better."
A little bit more time reading up on the subject rather than spouting your wildly inaccurate Armchair Psychiatrist views would do us all a favour, Edmund.
Phil Sawyer, Birmingham, UK
It would have been ironic if they had tested this drug on humans...
Colin, Norwich, UK
I've got a much cheaper solution!
If you have to leave it alone too long, don't get a dog.
starling, Lancaster,
I think the drugs are very much long overdue for our faithful knine friends. Actually that is the least we can do after we have subjected them to so much undue stress by labeling them with expressions like: a dog's breakfast, dog eats dog, dog tired, sick as a dog, put in the dog house etc. We are lucky that they haven't taken us to court for harassment otherwise they can collar the lot of us and we will all end up in the dock.
Wing, Poole, UK
"We're thrilled that our first product for dogs can help restore the human-pet bond."
How exactly? Surely if you can ignore your dog and prevent its 'annoying' cries for attention by medicating it, how will that restore the human-pet bond? This provides people with no natural insentive to look after their animals.
Tom, London, UK
Wow,
I've got a dog (7 years old) whose behavior has become increasingly unpredictable, to the point where my wife and I are considering having him put down. It's scary, because he's nice and mellow 99 percent of the time, but then there's that 1% where he'll bark aggressively at a young woman or an elderly man or whoever walking by doing nothing wrong. We're worried he's going to hurt someone, but he's like a son to us, and the thought of killing him makes me ill. If there's a drug out there that will modify his behavior, I'll give it a shot before the alternative. I wouldn't want to pass this unpredictable dog off to anyone else either(Like finding a different home for him); this is our problem, not anyone elses'(Yet!).
JA, Menomonie,
Just what is a 'small minority'? 5%? 10%? It could be that Eli Liily had better get ready for lawsuits when this 'small minority' has 'fits' and destroys property and perhaps attacks people. Prozac for dogs seems another case of using a chainsaw to cut butter.
pankaj seth, London, Canada
Clearly, Edmund Dantes, you've never suffered from clinical depression. What if "the problem" as you refer to it is not a lack of bunnies, hugs and sunshine, but an imbalance of serotonin in the brain? In other words, if most depression is caused by an organic problem that can be corrected, why should people amenable to taking drugs to correct it be denied them? Are antibiotics "disgusting"? Insulin? Pain medication for cancer patients? Meds for schizophrenia? (Maybe those people should just get over themselves and ignore the voices?) If you don't like antidepressants, don't take them.
T. Roth, Danbury, CT, USA
This is absolutely disgusting. Medicating people because they experience normal emotions is absurd. The main problem with the USA and GB is that most people are medicated and mentally unstable.
Here is a novel idea lets try to deal with the problem that causes the depression instead of ignoring the problem and popping a pill.
Edmund Dantes, Connecticut, USA
miracle at last¡¡¡¡¡ animals also feel and suffer the same as humas, it's already time to begin caring about them as they deserve. I hope this will serve right for a smooth and effective relief for their suffer, sometimes as an aftermath of contagion by their unfortunate owners. God bless this and more¡¡¡¡ If it is rightly used, at least it will be a good utility at home and vet's
Kevin Lowell, Newcastle, England
this is robbery and exploitation, drugging pets instead of caring for them
mini, gateshead, england