Mark Henderson, Science Editor
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Genetically modified crops will be the only sustainable way of solving Britain’s dietary shortcomings, scientists claim.
Barely one in four British adults consumes close to the recommended quantities of critical omega3 fatty acids found chiefly in oily fish. Genetic engineering is the sole practical means of getting more of them into the food chain without damaging fragile fish stocks, researchers said.
Two long-chain omega3 acids, EPA and DHA, are known to play important roles in health, protecting against heart disease, diabetes and hypertension and promoting the growth of brain cells in the young.
Both acids, however, are produced only by algae and reach the human body through the fish that eat them, or from meat, milk or eggs from animals reared at least partly on fish meal. Raising dietary levels of the nutrients would thus place further pressure on fisheries that are already under threat.
Crops enhanced with genes from algae, however, can make DHA and EPA. These can then be used as feed to boost the quantities found in chicken and other animal products.
Experimental GM linseed and oilseed rape have been produced at Rothamsted Research, in Hertfordshire, which expects to seek regulatory approval for commercial use within three to five years.
In the longer term, it may be possible to produce GM crops with omega3 acids that could be eaten directly, allowing vegetarians to benefit from the nutrients that are usually almost absent from their diets.
Professor Johnathan Napier, who leads the Rothamsted team, said that GM was the only way of making DHA and EPA in crops, because the genes that allow their synthesis existed only in marine micro-algae. “That’s why we have to take the GM route. There is no alternative,” he said. “We can’t use mutagenesis or conventional breeding – the genes aren’t there in crop plants in the first place.”
While the Government recommends consuming 450mg of the acids daily, average consumption is only 244mg, according to research by the European Union Lipgene project, which is investigating links between nutrition and cardiovascular disease and diabetes.
Most people’s intake falls well below even this level, as 70 per cent of British adults never eat oily fish, such as salmon, mackerel, herring and fresh tuna. The problem could be addressed if people were to eat a portion of oily fish each week, through supplements or through chicken and other meat that has been enhanced with DHA and EPA.
In each case, however, the acids would have to come ultimately from wild fish, placing unsustainable pressure on fisheries. Farmed fish are no solution, as they are fed on fish meal and oil that comes from wild sources.
Lipgene research has indicated that people are open to accepting GM technology if it has clear nutritional and environmental benefits.
“There has been a lot of concern and resistance about GM technology in the food chain, but things can change,” said Professor Ian Givens, of the Nutritional Sciences Research Unit at the University of Reading.
“When the issue about sustainability of fish oils becomes clearer and people can see more clearly what the benefits are from this sort of approach, I suspect mindsets will change.”
Professor Judy Buttriss, of the British Nutrition Foundation, said: “The project has looked at consumer attitudes to GM, and we were quite surprised to see that there was openness when people could see benefits for themselves and their families.”
Professor Napier said: “There isn’t an alternative to this. The question is, where are you going to source these fatty acids if your only source is in decline and unsustainable. You can’t just be a naysayer.”
Oiling the wheels
— There are two long-chain, polyunsaturated omega3 fatty acids that play important roles in human health: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)
— Both reach the human food chain only through oily fish, such as salmon, mackerel, herring and fresh tuna. Canned tuna is low in the acids. The fatty acids are created originally by marine algae, which are then eaten by fish
— Research has established firmly that EPA and DHA protect against conditions such as type 2 diabetes, heart disease and high blood pressure, which together are known as “metabolic syndrome”
— DHA is also involved in brain development, in the formation of nerve cells during the last trimester of pregnancy in the first year of life. Some evidence also suggests that it protects against cognitive decline and dementia in the elderly
— Official recommendations are for adults to consume 450mg of the acids daily, the equivalent of a portion of oily fish once a week. The average intake in Britain is only 244mg, and most people consume much less than this as 70 per cent of the population do not eat oily fish
Source: Lipgene

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James is right. And while humans have the ability to convert the short chain omega 3's (ALA) found in flax to the longer chain (DHA, EPA), the conversion in the human body is not very efficient and thus in order to see a benefit, a direct intake of DHA and EPA is required.
"A simple change of diet from cooked, processed foods, to a natural one of raw, will produce miracles." That is exactly what this will enable us to do. It will come right from the plant.
The organic lovers seem a bit quick to judge. There are many 'natural' chemicals that are bad for us, being 'natural' does not mean it is safe. Sometimes synthetic versions of natural chemicals are less toxic then their natural counterpart.
Despite most people knowing that fish is good for them, people are still not eating enough because they just don't like the taste. Other alternatives such as this, just may help the cause!
J Elliott, Canada,
GM technology is purely profit-driven. The general population is bamboozled at the science, when it doesn't have to be.
A fine book from the 1050's - the Elixir of Life, showed that scientists around the world, in laboratories and hospitals, with actual patients, could restore health to obstinate longstanding illnesses, by the mere application of RAW, natural fruits and vegetables ! The same results were also shown with ANIMALS - removing the placebo effect.
This simple approach (you could call it Nature Cure, which has been going for almost 200 years) is all it takes. But there is no money in for the biotech companies or medical industry and therefore they don't want to know.
A simple change of diet from cooked, processed foods, to a natural one of raw, will produce miracles. No drugs at all. And that is what the biotech companies do not like!
Man wasn't brought onto the planet with scientific data on nutrition. And he doesnt need it if he eats raw.
Dave Warren
Dave Warren, EDINBURGH, Scotland, UK
Excellent cant wait for it to get in the shops. GM is a fantastic technology being increasingly used all over the world . One thing among many others that the billions on this planet needs to keep them fed, bring it on and stop ripping off the oceans.
adam carpenter, london,
Francesca's comment is a common misunderstanding. The important difference between plant (e.g. flax) and fish oils is the length of the hydrocarbon fatty acid chain. Flax omega-3 oils are only 18 carbons in length and EPA and DHA are 20C and 22C, respectively, and these long chain omega-3 oils are especially important in human metabolism.
James, Canberra, Australia
I think it's quite well known from everybody that flaxseed oil or linseed oil, which are vegetable oil, and of course suitable also for vegetarian, are a high source of Omega3...so how is it possible that an "expert" says the only source of Omega3 is animal?
Cheers
Francesca, London/Verona, UK/IT
I've never heard anything as ridiculously biased as this from a 'scientist' before. Scaremongering about a ficticious lack of Omega-3 sources in order to pretend GM science is essential?? I doubt anyone will see this as anything other than ridiculous propaganda and I'm surprised at The Times for not putting this in some sort of perspective. "No alternative"? - rubbish!!
There is no shortage of Herring or Mackrel in the UK - it's a vastly underexploited resource and it would be far better to encourage people to eat more of it, which would help our beleagured local fishing industry too, rather than mess about with the basic building blocks of our food-chain, with no real idea of where it will lead us.
John Willis, Edinburgh, Scotland
Are the experts saying that we are having a food shortage? Or a vitamin/mineral etc. shortage in our food, because the two are different. If there is a shortage of vitamin/mineral etc. in the food, then perhaps it may be an idea to find out why? For example, if farmed salmon is deficient in nutrients, why farm it? The whole subject of food needs more research, and not just from the standpoint of profit, but from the standpoint of "is it fit to eat?' and does it's product effect the environment in a detrimental way. This includes what cattle and pigs eat and are innoculated with; it includes what level of pollution are in our seas for fish to absorb and so on. Better late than never!
Tarni, London, UK
ALL GM FOOD IS GUILTY UNTIL PROVEN INNOCENT. No one â scientist, or citizen - will know for certain if GM food will cause long term damage to the fauna and flora of this world â especially children who seem to be vulnerable to the food additives which are present in todayâs food â for as long as one, or two generations. By then it will be too late and no amount of apology will get the genie back in the bottle. It is very influential corporations who seem to be able to con governments, who are the real villains here.
Richard, Oxford, Oxfordshire
The problem with this article, as is so often the case with reporting on genetic engineering (GE), is what is left unsaid by Prof. Napier. There are many excellent vegetable sources of the omega3 fatty acid ALA (especially good ones are flax seed and several tree nuts), which the body may then convert to the needed types of omega3. The problem is that we sometimes consume too much of omega6 fatty acids, which slow the conversion process. This may be remedied by simple dietary changes. But I suppose common sense is more difficult for GE corporations to sell.
Doug Gurian-Sherman, Ph.D., Washington, DC
I cannot believe this. What's wrong with just eating fish? And if you can't do that as you're vegetarian or whatever, why not just supplement with fish or krill oil?!
Organic food is far richer in nutrients, lacks the revolting chemicals inundating us through food, cleaning products, cosmetics, skin 'care', teflon, etc etc, and is grown how it's meant to be, the way nature intended.
GM crops are NEVER the solution; they're proven in a number of independent (ie not industry funded) studies to be dangerous, harmful, and pollute conventional and organic crops with their synthetic material. They are insidious, dangerous, and downright scary.
Organic is the only way we can sustain our foodstuffs.
And re-education on eating properly is the only way to solve Britons' diet failings.
Follow the money trail.
Erin, Chichester, UK,
"Common Sense?" This discussion shows that is a rarer commodity than the omega 3 fatty acids we need. Seems to me, that the people who never give up are the ones who keep their heads in the sand and believe that if they stay in that position they are doing something useful: rejecting anything new, especially if it is the product of science or horrors, a corporation. This is a nice idea if you want to live in a cave eating berries. Common sense tells me to try and judge ideas on their merit, not their provenance. Not all corporate ideas are any good, not all are bad. Not all of the ideas that come from Prince Charles are any good either.
By the way, if we want to throw the "Frankenfood" label around, better include much of the organic produce as well: the majority of rice and wheat, organic as well as "conventional" is derived from radiation and chemical mutagenesis bombardments started in the 50s and 60s. Whoops.
Elliot Entis, Boston,
force feed gm concentrates to these fools for two years and if there is no reaction i may just and i mean
just consider eating a tiny amount
ps and i farm 1020 acres
p w johnstone, aberdeenshire, uk
So what about the generations of humans who didn't live near the sea or whose communities didn't do fishing? What did they do for Omega3
Inge Jones, London, UK
I can't help but think you need to know the science before you can see the potential for catastrophe, or lack thereof. Why is it that people comment without seeming to have understood what the article is about? The oily fish are not enough because catching the amount needed to satisfy everyones recommended dose of omega 3 would see them rapidly decline.
Nicholas Lee - Do you really believe taking money away from R&D and putting it into farms in this country (why just this country?) would make the whole world happier and better-fed?
I am not sold on the need for omega 3 crops as the majority of the UK population who don't get the recommended dose seem to be doing OK. However I do believe that they would achieve what the scientists are claiming: a reduction in the need to catch oily fish to meet peoples recommended dietary requirements.
Believe it or not the experts are exactly that and know what they are talking about. You do not.
I Moss, Edinburgh, UK
Surely anyone with any common sense can see the potential catastrophe in this?
Even Hollywood can understand...
God creates man, man creates dinosaurs, man destroys God, dinosaurs eat man.
W Smith, Oldham,
How about the alternative of " oily fish " for omega 3 oils ? There are several oily fish suggested as a source in your article , why is this not enough ?
Benzo, Nr Chelmsford,
They never give up, do they? I would have more time for the opinion of so-called 'experts' if so many of them did not depend on corporate funding their research. We do not need GM foods, and if governments spent a third of the money on supporting their own farmers that they spend on promoting these Frankenstein foodstuffs, the world would be a happier and better-fed place. Organic is the route to go.
Nicholas Lee, Windsor,, UK